Currently Enrolling Trials
The ACTIV-6 research study is testing several medications that are already approved for other diseases to see if they can help people with mild to moderate COVID-19 feel better faster and stay out of the hospital.If you are 30 years old or older, have tested positive for COVID-19 within the past 10 days and have […]
PREVENTABLE is one of the largest research studies in older adults. The purpose is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. A statin is a commonly used drug to lower cholesterol. Are you a good fit for PREVENTABLE? Contact the study […]
Vaccinated for COVID-19? If you work in health care and received a COVID-19 vaccine, please consider joining a new research study called HERO-TOGETHER. By joining HERO-TOGETHER, you can help the public understand how people do after vaccination. Join at heroesresearch.org/together !
The STAR CRN, a member of PCORnet – the National Patient-Centered Clinical Research Network, encompasses eight health systems servicing three main regions: 1) Vanderbilt University Medical Center(VUMC), 2) the Vanderbilt Health Affiliated Network (VHAN), 3) Meharry Medical College (MMC), 4) Duke University Health System, 5) University of North Carolina at Chapel Hill, 6) Wake Forest Baptist Health, 7) Health Sciences of South Carolina, and 8) Mayo Clinic, headquartered in Minnesota. With data on over 14 million patients, the STAR CRN network consists of academic health centers, community hospitals and a range of outpatient practices including primary care, specialty practices and safety net facilities that serve diverse populations. Through this network, we have access to a broad array of clinical data, informatics tools, patients, providers, and systems to address an array of research questions. The objective of our CRN is to robustly support comparative effectiveness studies, pragmatic clinical trials, health system innovation, and the other research needs of our stakeholders and partners. Our network is particularly focused on research to improve health in the southern United States which has the highest rates of obesity, diabetes, cardiovascular disease, certain cancers, and other conditions, as well as significant disparities in health status and health care delivery.
The STAR Stakeholder Engagement Team ( SET) Leads implementation of the people-centered engagement plan; identify and engages a variety of stakeholders (patients, caregivers, clinicians). This group is comprised of members faculty and staff managing stakeholder engagement at CRN-level, site stakeholder engagement reps (i.e., staff or faculty) and designated patient representatives across the institutions in STAR-CRN . They closely collaborate with Stakeholder Advisory Council members and serve to facilitate implementation of stakeholder engagement.
The STAR Stakeholder Advisory Council (SAC), consists of patients, community members, and clinicians who help prioritize research opportunities and review all incoming studies to ascertain engagement of patients. Input from stakeholders is used to inform the research design, implementation, analysis, dissemination and/or priority setting. The SAC review of research products entails a quantitative, objective and validated measure of the Person Centeredness of Research ( PCoR) score. This measurement tool is the first of its kind and available to other Networks within STAR for measuring.
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VUMC receives $28 million to lead national study of COVID-diabetes link | VUMC Reporter | Vanderbilt University
Vanderbilt University Medical Center has received a $7 million, five-year funding award from PCORI (Patient-Centered Outcomes Research Institute) to compare two sedatives used to place breathing tubes in the emergency department (ED) or intensive care unit (ICU).
STAR CRN is happy to announce our upcoming Quarterly Update on July 27, 2023, at 1 pm CST.
ADAPTABLE, the first demonstration project of PCORnet®, the National Patient-Centered Clinical Research Network, has been named by the Clinical Research Forum as a Top 10 Clinical Research Achievement Awardee for 2022. The awards celebrate outstanding achievements and major advances in clinical research from across the U.S. Honorees were selected by a panel that considered clinical research studies […]
The STAR Clinical Research Network, based at Vanderbilt University Medical Center, has been approved for an additional $8.9 million in funding from the Patient-Centered Outcomes Research Institute (PCORI) to support its efforts to improve health care throughout the Southeast and across the United States. The funding will be provided over three years as part of […]
When publishing or presenting work created from STAR CRN data or resources, we require the use of the following citation:
For the time period before 6.30.2019: “The STAR CRN, formerly Mid-South CDRN was initiated and funded by Patient-Centered Outcomes Research Institute (PCORI) through the contract CDRN-1306-04869 , the Vanderbilt Institute for Clinical and Translational Research with grant support from (UL1TR002243 from NCATS/NIH), and institutional funding.”
For the time period 12.1.2018-12.31.2019: “The STAR CRN was initiated and funded by People-Centered Research Foundation (PCRF) through the contract PCRF RFA 2017-12-05, the Vanderbilt Institute for Clinical and Translational Research with grant support from (UL1TR002243 from NCATS/NIH), and institutional funding.”
For the time period 1.1.20 and going forward: “The STAR CRN was initiated and funded by Patient-Centered Outcomes Research Institute (PCORI) through the contract RI-CRN-2020-009, the Vanderbilt Institute for Clinical and Translational Research with grant support from (UL1TR002243 from NCATS/NIH), and institutional funding.”